The Center for Computational Imaging and Simulation Technologies in Biomedicine

CISTIB is an international and interdisciplinary research centre in the School of Computing - Faculty of Engineering - at the University of Leeds. The research group was established in Zaragoza in 2001 and in 2004, relocated to Barcelona to the Universitat Pompeu Fabra (UPF) during which time CISTIB continued to evolve through the integration of new areas of image acquisition, computational physiology, treatment simulation, biomedical information management and software development.

Initially, the research was mainly focused on computerised biomedical image analysis, with an emphasis on the cardiovascular system (including the cerebro-vascular sub-system), however CISTIB quickly expanded and broadened the research to include converging technologies from other areas.

In 2012, the group relocated to the University of Sheffield, where it continues to focus on the development of computational medical imaging


and simulation techniques, with emphasis on angiology, cardiology, neurology and orthopaedics. The group's main objective is the consolidation of a solid scientific base regarding the acquisition, analysis, and post processing of medical images and simulations. The group's strategy followed the lines reflected in the Virtual Physiological Human (VPH) concept, and today the group plays an active role in VPH projects, including, leading on the €18 million, 20 partner FP7 funded project VPH-DARE@IT www.vph-dare.eu


The group, currently comprising 30 members of staff, is located in the Pam Liversidge Building, a new development in the university’s Faculty of Engineering, which is home to international, collaborative, inter-disciplinary research groups.

HEADER Engineering and Physical Sciences

During the 13 years of operation, CISTIB has grown considerably and has received recognition for its activities and achievements on an international level. This recognition includes:

  • In November 2013, Prof. Frangi, was named an IEEE Fellow. He has been recognised for contributions to medical image analysis and image-based computational physiology.

  • Catalan Research Excellence Group: recognised as an Established Research Group (2009-2013).

  • Research Excellence Group in Bioengineering recognised at state-level: through its involvement, from its founding, in the Networking Biomedical Research Centre (CIBER) in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN; www.ciber-bbn.org) financed by the Instituto de Salud Carlos III.

  • VPH European Research Excellence Group: CISTIB is founding member of the VPH Network of Excellence. This network of excellence is formed by a number of pioneering European groups promoting clinical translation as part of the Physiome.

  • Centre TECNIO: TECNIO is the umbrella name devised by ACC1Ó and set up with the aim of bringing together leading experts currently working in applied research and technology transfer in Catalonia. The Catalan Innovation Agency, ACC1Ó has acknowledged the CISTIB's transfer of technology to industry.

  • Leadership in excellence with a translational focus: under the present direction of Prof. Alejandro Frangi, the centre boasts of the experience of a researcher who has been awarded prizes of local and international prestige.

  • Prof. Frangi received the IEEE Engineering in Medicine & Biology Early Career Award (2006), being the first Spanish-based researcher to do so